COURSE OUTLINE

 

·       Virulence and its measurement

·       Mechanisms of bacterial pathogenicity Adherence/persistence, Types of adherence factors Enzymes- hyaluronidase, lipases, collagenase etc Toxigenicity, Exotoxins, Endotoxins

Antibiotic resistance Oncogenesis

·       Stages of an Infection

·       Mechanism of host resistance

Non- specific host resistance: mechanism and physiological barriers Role of normal flora in health and disease

·       Enzymes as Biocatalysts

·       Isolation and identification of major bacterial pathogens: Identification of appropriate specimen, Collection of specimens

Processing of specimen- microscopy, use of selective and differential media, enrichment media etc, incubation temperatures aerobic and anaerobic incubation Identification of organisms- morphological characteristics, biochemical characteristics, immunological methods, nucleic