COURSE OUTLINE

 

TOPIC 1: Virulence and its measurement
TOPIC 2: Stages of an Infection
TOPIC 3: Mechanisms of bacterial pathogenicity

Adherence/persistence, Types of adherence factors Enzymes- hyaluronidase, lipases, collagenase etc Toxigenicity, Exotoxins, Endotoxins, Antibiotic resistance               ,,,,    Oncogenesis

TOPIC 4: Enzymes as Biocatalyst

TOPIC 5: Microbial Mechanisms of Pathogenicity: How Microorganisms Cause Disease Sexually Transmitted Diseases

    Non- specific host resistance: mechanism and physiological barriers.  Role of normal flora in health and disease.

TOPIC 6: Isolation and identification of major bacterial pathogens: Identification of appropriate specimen, Collection of specimens

Processing of specimen- microscopy, use of selective and differential media, enrichment media etc, incubation temperatures aerobic and anaerobic incubation Identification of organisms- morphological characteristics, biochemical characteristics, immunological methods, nucleic.