ADVANCED PHARMACEUTICAL MICROBIOLOGY: MCB 806

GODFREY OKOYE UNIVERSITY

DEPARTMENT OF BIOLOGICAL SCIENCES

MCB 806: ADVANCED PHARMACEUTICAL MICROBIOLOGY (3UNITS)

LECTURER: DR. RUTH AFUNWA

COURSE CONTENT

Antibiotics and Antimicrobial agents, origin, development and future prospects, ethnomedical research, types of antibiotics and synthetic antimicrobial agents, natural antimicrobial agents, policies in ethnomedical research standardization of natural plant products, usage and control in pharmaceutical and hospital outfits. Prospects for novel drug discovery. Manufacture of and assessment of new antibiotics, principles and methods of antibiotic assay. Mechanism of action, and microbial resistance to antibiotics. Chemical disinfectants, antiseptics and preservatives. Evaluation of non-antibiotics/antimicrobial agents. Mode of action, resistance to non-antibiotic/antibacterial agents. Pharmaceutical products of microbial biotechnology. Microbial spoilage and preservation of pharmaceutical products. Contamination of non-sterile pharmaceuticals in hospitals and community environments. Principles of sterilization, control, sterility testing quality

 

S/N

COURSE OUTLINE

 

 

1.

 

INTRODUCTION:                Origin, development, future aspects and

                                                 ethno medical research

 

2.

 

TYPES OF ANTIBIOTICS:  Natural antimicrobial agents, synthetic  

                                                 antimicrobial agents,

                                                 Policies in ethno medical research,

                                                 Standardization of natural plant products,

                                                 Usage and control in pharmaceutical and  

                                                 hospital outfits, prospects for novel drug  

                                                  discovery           

 

3.

 

SYNTHESIS:                          Manufacture and assessment of new antibiotics,  

                                                  Principles and methods of antibiotic assay, 

                                                  Mechanisms of action ,

                                                  Microbial resistance to antibiotics      

 

4.

 

ANTISEPTICS, DISINFECTANTS

&PRESERVATIVES:            Evaluation of non antibiotics and antimicrobial 

                                                  agents, mode of action,

                                                  Resistance to other antimicrobial agents

 

5.

 

PARENTERAL ROUTES OF DRUG ADMINISTRATION 

                                                Contamination in the hospitals and environment

 

 

6.

 

STERILIZATION:               Principles of sterilization, control, sterility testing,

                                                Quality assurance.  Factory and hospital  

                                                Hygiene and Good manufacturing practice

MICROBIAL SPOILAGE

&PRESERVATION:            Preservation of pharmaceutical products,